Early Treatment for Acute ACL Tear
Completed · Phase 2 · Has a placebo group
Conditions studied: Anterior Cruciate Ligament (ACL) Tears
In brief
This research study is the first of its kind and will allow health care professionals and researchers to answer many questions about the reasons why anterior cruciate ligament (ACL) injury leads to knee pain and disability and osteoarthritis. We also hope that this study will be the beginning of new, more powerful and safer drugs to help patients with ACL injuries heal sooner and return to sports or daily activities pain free. Study participants will be recruited from the University of Kentucky and Vanderbilt University. The purpose of this research is to gather information on how safe and effective Kenalog® is in alleviating knee pain following ACL rupture.
Key facts
- Study ID
- NCT01692756
- Run by
- Cale Jacobs
- People needed
- 49
- Starts
- 2013-03-01
- Expected to finish
- 2017-02-05
- Last updated by the study team
- 2018-12-05
Who can join
Age: 14 and older, up to 33. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- currently participating in sporting activities
- Normal contralateral knee status
- Anterior Cruciate Ligament (ACL) injury occurred while playing a sporting activity
You may not qualify if…
- underlying inflammatory disease (i.e. Rheumatoid Arthritis, Psoriatic Arthritis, etc.)
- have been diagnosed with hepatitis B or tuberculosis
- currently have an infection, including infection of the skin
- have a disease that weakens your immune system such as diabetes, cancer, HIV or AIDs
- other major medical condition requiring treatment with immunosuppressant or modulating drugs.
- A history of chronic use of non-steroidal anti-inflammatory drugs
- previous exposure or allergic reaction to Kenalog
- prior knee surgery (Ipsilateral or contralateral)
- have received any investigational drug with 4 weeks of study Visit 1
Where it is running
- UK HeathCare Sports Medicine — Lexington, Kentucky, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.