Effect of Ticagrelor vs. Dipyridamole on Adenosine Uptake

Completed · Phase 1 · Has a placebo group

Conditions studied: Coronary Artery Disease

In brief

The investigators are trying to determine if a single dose of Ticagrelor will increase delivery of intraarterially-infused adenosine into the forearm interstitium, consistent with adenosine reuptake blockade.

Key facts

Study ID

NCT01690884

Run by

Vanderbilt University

People needed

28

Starts

2012-08-01

Expected to finish

2017-01-01

Last updated by the study team

2018-02-28

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subjects will be healthy volunteers, without significant pulmonary, cardiovascular gastrointestinal, hematological or renal diseases
• Not taking any regular medications
• Able to provide signed consent prior to study participation.

You may not qualify if…

• History of asthma
• Pregnancy
• Exposure to an investigational drug in the last 2 months.
• Known hypersensitivity to study medications

Where it is running

• Autonomic Dysfunction Center — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

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