Transcranial Magnetic Stimulation Effects on Nicotine Craving

Completed · Not applicable · Has a placebo group

Conditions studied: Nicotine Dependence

In brief

The proposed study will measure the change of cortical excitability during nicotine craving and examine the effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on nicotine craving and cue-reactivity among adult regular smokers.

Key facts

Study ID

NCT01690130

Run by

Medical University of South Carolina

People needed

19

Starts

2009-06-01

Expected to finish

2014-02-01

Last updated by the study team

2020-04-01

Who can join

Age: 18 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Right handed males and females, between the ages of 18 and 50
• Daily smokers who smoke at least 10 cigarettes per day for at least past 1 year
• Mentally capable of reading, writing, giving consent, following instructions

You may not qualify if…

• history of seizures
• taking medications that lower seizure threshold
• implanted metal devices (e.g., pacemakers, metal plates, wires)
• pregnant
• history of brain surgery or history of loss of consciousness >15 minutes
• any unstable major axis I psychiatric disorder in the past month (e.g. psychotic disorders)
• Current substance use disorders other than nicotine and caffeine use, in the past 30 days
• Any medication (e.g., propranolol) or unstable medical condition that may interfere with psychophysiological (e.g., heart rate) monitoring

Where it is running

• Medical University of South Carolina — Charleston, South Carolina, United States

Full record on ClinicalTrials.gov

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