Serum Vasopressin Levels and Severe Hemorrhagic Shock

Withdrawn before enrolling

Conditions studied: Injury

In brief

The purpose of this study is to determine if vasopressin is used up by the body during traumatic shock (severe low blood pressure due to trauma).

Key facts

Study ID

NCT01676454

Run by

Poudre Valley Health System

People needed

0

Starts

2012-11-01

Expected to finish

2013-01-01

Last updated by the study team

2018-05-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with a minor injury or injuries, defined as:
• no episodes of systolic blood pressure < 90 mmHg between occurrence of injury and admission;
• no blood transfusion requirement;
• base deficit < 5 mEq/L;
• no requirement for mechanical ventilation other than transiently during orthopedic surgery.

You may not qualify if…

• Pregnancy
• corticosteroid use,
• prisoners, and/or
• head trauma as determined by computed tomography (head trauma may itself induce diabetes insipidus, a marker of pituitary damage and vasopressin deficiency), and/or
• evidence of spinal cord injury (another cause of vasodilatory shock).
• Patients will also be excluded if pre-hospital provider information cannot be obtained, or indicates that the trauma occurred more than one 1 hour prior to emergency department admission.

Where it is running

• Medical Center of the Rockies — Loveland, Colorado, United States

Full record on ClinicalTrials.gov

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