The Role of Gadoxetate (Eovist) Enhanced CT in Evaluating Cholangiocarcinoma
Completed · Early Phase 1
Conditions studied: Cholangiocarcinoma
In brief
The purpose of this project is to evaluate the role of gadoxetate (Eovist®) enhanced dual-energy CT in better evaluating perihilar cholangiocarcinoma. This pilot project aims to address a long-term pitfall in the imaging of cholangiocarcinomas, by providing higher resolution delineation of these often infiltrative tumors on single-source, Dual-Energy Spectral Multi Detector CT (MDCT), capitalizing on improved spatial resolution achievable with MDCT compared to MRI and at the same time producing a non-invasive CT cholangiogram to aid in accurate diagnosis and treatment planning of cholangiocarcinoma, particularly, the hilar variety.
Key facts
- Study ID
- NCT01673802
- Run by
- University of Alabama at Birmingham
- People needed
- 18
- Starts
- 2012-08-01
- Expected to finish
- 2014-01-01
- Last updated by the study team
- 2017-06-01
Who can join
Age: 19 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Subjects will be adult (age 19 or older) with suspected cholangiocarcinoma of the liver.
- Subject must be able to provide a written informed consent.
- Subject will be scheduled for gadoxetate contrast enhanced MRI scan of the liver (obtained as part of usual clinical practice).
You may not qualify if…
- Standard MRI safety screening criteria will be employed, and subject will be excluded if any contraindications to undergo MRI are met.
- Subjects with metallic biliary stents or multiple peripancreatic surgical clips on abdominal MDCT will be excluded.
- Subjects on hemodialysis or with glomerular filtration rate (GFR) less than 30 will be excluded.
- Subjects will not be excluded on the basis of gender, race, ethnicity, or religion.
- Subject may not be pregnant or lactating.
Where it is running
- University of Alabama at Birmingham — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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