Simtuzumab (SIM, GS-6624) in the Treatment of Cirrhosis Due to NASH
Stopped early · Phase 2 · Has a placebo group
Conditions studied: Liver Fibrosis Due to NASH
In brief
The primary objective of this study is to evaluate the safety and efficacy of SIM (formerly referred to as GS-6624) in adults with compensated cirrhosis due to Non-Alcoholic Steatohepatitis (NASH). It will consist of 2 phases: * Randomized Double-Blind Phase * Open-Label Phase (optional)
Key facts
- Study ID
- NCT01672879
- Run by
- Gilead Sciences
- People needed
- 259
- Starts
- 2012-10-29
- Expected to finish
- 2017-01-03
- Last updated by the study team
- 2019-03-27
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Southern California Liver Centers — Coronado, California, United States
- University of California, San Diego (UCSD) — San Diego, California, United States
- University of California San Francisco (UCSF) — San Francisco, California, United States
- University of Colorado, Denver — Aurora, Colorado, United States
- University of Miami — Miami, Florida, United States
- Tampa General Hospital — Tampa, Florida, United States
- Northwestern University — Chicago, Illinois, United States
- Indiana University School of Medicine, Division of Gastroenterology/Hepatology — Indianapolis, Indiana, United States
- Iowa Digestive Disease Center — Clive, Iowa, United States
- University of Louisville — Louisville, Kentucky, United States
- Tulane University — New Orleans, Louisiana, United States
- Mercy Medical Center — Baltimore, Maryland, United States
- Walter Reed National Military Medical Center — Bethesda, Maryland, United States
- Lahey Clinic — Burlington, Massachusetts, United States
- University of Mississippi Medical Center — Jackson, Michigan, United States
- Minnnesota Gastroenterology, PA — Saint Paul, Minnesota, United States
- Saint Louis University Hospital — St Louis, Missouri, United States
- State University Of New York at Buffalo — Buffalo, New York, United States
- North Shore University Health System — Manhasset, New York, United States
- New York University — New York, New York, United States
- Columbia University Medical Center — New York, New York, United States
- Duke University Medical Center — Durham, North Carolina, United States
- University Hospitals Case Medical Center — Cleveland, Ohio, United States
- University of Pennsylvania Hospital — Philadelphia, Pennsylvania, United States
- Mayo Clinic Hospital — Phoenix, Arizona, United States
Full record on ClinicalTrials.gov
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