Effects of Egg Ingestion on Endothelial Function in Adults With Coronary Artery Disease

Completed · Not applicable

Conditions studied: Coronary Artery Disease

In brief

The purpose of this study is to determine the effects of daily consumption of eggs or egg substitute for 6 weeks on endothelial function and on cholesterol and lipoprotein levels in participants with clinically established coronary heart disease (CHD).

Key facts

Study ID: NCT01672567
Run by: Griffin Hospital
People needed: 34
Starts: 2010-10-01
Expected to finish: 2012-04-01
Last updated by the study team: 2020-03-26

Who can join

Age: 35 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Males age greater than 35 years;
Post-menopausal females not currently on hormone replacement therapy;
Non-smokers;
CVD as defined by the presence of at least one coronary stenosis >50% determined angiographically or a documented history of myocardial infarction.

You may not qualify if…

Failure to meet inclusion criteria;
Anticipated inability to complete study protocol for any reason;
Current eating disorder;
Use of lipid-lowering or antihypertensive medications unless stable on medication for at least 3 months and willing to refrain from taking medication for 12 hours prior to EF scanning;
Regular use of high doses of vitamin E or C;
Use of insulin, glucose-sensitizing medication, vasoactive medication (including glucocorticoids, antineoplastic agents, psychoactive agents, or bronchodilators) or nutraceuticals;
Regular use of fiber supplements;
Diabetes;
Sleep apnea;
Restricted diets by choice (i.e., vegetarian, vegan);
Coagulopathy, known bleeding diathesis, or history of clinically significant hemorrhage; current use of warfarin.

Where it is running

Griffin Hospital — Derby, Connecticut, United States

Full record on ClinicalTrials.gov

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