Hypobaria and Traumatic Pneumothorax

Completed

Conditions studied: Pneumothorax

In brief

The purpose of this research is to see if people who have had a collapsed lung that has been re-expanded can be safely taken to an elevation that a person might experience while in a commercial airplane without having their lung partially collapse again, or have any symptoms such as feeling short of breath or having oxygen levels in the blood decrease while at the simulated altitude. The investigators hypothesize that subjects who have had a collapsed lung that has been re-expanded will not have any adverse symptoms or signs while subjected to a simulated altitude of 8400 feet (565mm Hg) or 12650 ft (471mm Hg).

Key facts

Study ID

NCT01670942

Run by

Intermountain Health Care, Inc.

People needed

20

Starts

2012-10-01

Expected to finish

2013-12-01

Last updated by the study team

2014-04-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Inpatient status on trauma surgery service
• An established diagnosis of pneumothorax with a traumatic etiology (patients with iatrogenic pneumothorax from attempted central venous line placement will be considered to have a traumatic etiology)
• Age ≥ 18 at the time of injury

You may not qualify if…

• Pregnancy
• Unable to give informed consent
• Pneumothorax which does not satisfactorily resolve after treatment with tube thoracostomy and requires operative intervention such as video assisted thoracoscopic surgery (VATS) or thoracotomy
• Pneumothorax requiring tube thoracostomy where the tube has been removed for < 4 or > 48 hours
• Head injury with GCS < 15 at time of evaluation for study
• Other injuries or conditions which would preclude participant's ability to remain in chamber for two hours
• NYHA class III or IV heart failure, active coronary artery disease, arrhythmias, pacemakers, implantable cardiac defibrillator, pulmonary hypertension, claustrophobia
• Severe obstructive or restrictive lung disease
• Chronic hypoxemia requiring supplemental oxygen
• Hypoxemia for any reason (pulmonary contusion, atelectasis, pneumonia, etc.) requiring > 3 liters supplemental oxygen at the time of entry into the study
• Inability to tolerate the confines of the chamber

Where it is running

• Intermountain Medical Center — Murray, Utah, United States

Full record on ClinicalTrials.gov

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