Effect of GnRH Antagonist vs Agonist Long on IVF Outcome, Peak Estradiol Level,and Duration of Stimulation

Completed · Not applicable

Conditions studied: Fertility

In brief

The purpose of this study is to determine if utilizing GnRH antagonists versus agonist long protocol during controlled ovarian stimulation (COH) with human-derived gonadotropins for assisted reproduction affects IVF outcome, peak estradiol level, and duration of stimulation.

Key facts

Study ID

NCT01669291

Run by

Main Line Fertility Center

People needed

43

Starts

2012-07-01

Expected to finish

2014-05-01

Last updated by the study team

2014-06-04

Who can join

Age: 21 and older, up to 40. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Ages 21-40 (inclusive up to 41)
• Day 2-4 FSH < or equal to 10
• Antimullerian Hormone (AMH) greater than or equal to 1.0
• Between 5 and 20 antral follicles on day 2-4
• Body Mass Index (BMI)>or equal to 18 and < or equal to 32

You may not qualify if…

• Smokers
• Polycystic Ovarian Disease
• Endometriosis greater than Stage I
• Testicular aspirated sperm

Where it is running

• Main Line Fertility Center — Bryn Mawr, Pennsylvania, United States

Full record on ClinicalTrials.gov

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