PET/CT in Psoriatic Arthritis
Completed
Conditions studied: Psoriatic Arthritis
In brief
When patients with psoriasis develop joint pain, it is often hard to decide whether or not the pain is due to psoriatic arthritis (PsA). At this time, doctors use information from the history and physical exam to determine the diagnosis. X-rays, magnetic resonance imaging (MRI) and ultrasound have been used to help with the diagnosis but all three have limitations. A newer imaging technique, whole body Positron Emission Tomography/Computed Tomography (PET/CT) uses the idea that inflammatory cells take up sugar to locate inflammation in the body. Because patients with PsA have inflammatory cells in their joints and tendons, this type of scan allows the physician to take a picture of the whole body and locate inflammation. The investigators have found that some patients with psoriasis (but without arthritis) have inflammation in joints and tendons even before the patient has symptoms. In this study, the investigators will explore how well PET/CT works for assessing inflammation in patients with PsA. This would be a very exciting tool that could be used to find and treat inflammation before it causes damage or pain.
Key facts
- Study ID
- NCT01654198
- Run by
- University of Pennsylvania
- People needed
- 12
- Starts
- 2012-07-01
- Expected to finish
- 2018-10-02
- Last updated by the study team
- 2020-12-08
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 18-80,
- active psoriatic arthritis (joint or enthesis inflammation)
You may not qualify if…
- Diabetes,
- pregnant,
- no active PsA
Where it is running
- University of Pennsylvania Division of Rheumatology — Philadelphia, Pennsylvania, United States
Full record on ClinicalTrials.gov
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