Pharmacologic MRI in Cocaine Addiction

Completed

Conditions studied: Cocaine Dependence

In brief

In the proposed study, the investigators will assess the brain response to medication probes the investigators have previously studied with SPECT. The brain response to ondansetron and lidocaine infusions will be measured Arterial Spin Labeling and functional connectivity MRI (fcMRI).

Key facts

Study ID

NCT01652378

Run by

University of Texas Southwestern Medical Center

People needed

12

Starts

2012-08-01

Expected to finish

2016-08-01

Last updated by the study team

2019-09-09

Who can join

Age: 21 and older, up to 64. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Cocaine dependence (cocaine patients)
• identify cocaine as their present primary drug of use
• Patients must have used cocaine within the previous 4 weeks (by patient history) and be abstinent for at least 1 week.
• No drug dependence (healthy control population).

You may not qualify if…

• Other medical or psychiatric disorders that may effect neural functioning.
• Medications that may effect brain functioning

Where it is running

• UT Southwestern Medical Center at Dallas, Divison on Addictions — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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