Functional Electrical Stimulation for Individuals With Secondary Progressive Multiple Sclerosis
Completed · Not applicable
Conditions studied: Secondary Progressive Multiple Sclerosis
In brief
Secondary progressive multiple sclerosis (SPMS) is a subtype of multiple sclerosis (MS) for which there are no existing therapies that alter the disease course. This research will utilize cutting edge functional electrical stimulation (FES) cycling technology with the goal of improving walking in individuals with SPMS. The investigators hypothesize that FES cycling will improve walking in subjects with SPMS.
Key facts
- Study ID
- NCT01647321
- Run by
- Johns Hopkins University
- People needed
- 16
- Starts
- 2012-07-01
- Expected to finish
- 2019-10-01
- Last updated by the study team
- 2020-03-19
Who can join
Age: 18 and older, up to 68. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- clinical diagnosis of secondary progressive multiple sclerosis
- males and females between the ages of 18 and 65 years
- Expanded disability status scale score between 5.0 and 7.0
- Able to consent to participate in study and are willing to undergo a lumbar puncture and blood draws
- If on on Ampyra or anti-spasticity agent, must be on stable dose for 1 month prior to screening
- No functional electrical stimulation use within 4 weeks
- Participants must be medically stable with no recent (1 month or less) inpatient admission for acute medical or surgical issues
You may not qualify if…
- Uncontrolled hypertension or other significant cardiovascular disease as determined by investigator
- History of epileptic seizures
- Subjects who have a pacemaker
- Relapse within thirty days prior to screening visit
- Pregnancy
- Subjects having a Stage 2 or greater sacral decubitus ulcer
Where it is running
- Johns Hopkins / Kennedy Krieger Institute — Baltimore, Maryland, United States
Full record on ClinicalTrials.gov
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