Role of the Supraspinal Opioidergic Circuit in Prefrontal TMS-Induced Analgesia
Completed · Not applicable · Has a placebo group
Conditions studied: Pain
In brief
Studies have shown that transcranial magnetic stimulation (TMS), a non-invasive form of brain stimulation, can reduce pain in the laboratory and in the clinic. The purpose of this study is to investigate how TMS relieves pain and affects pain circuitry in the brain. One of the primary study hypotheses is that opioid blockade will significantly reduce the pain relief produced by left prefrontal cortex TMS.
Key facts
- Study ID
- NCT01643798
- Run by
- Medical University of South Carolina
- People needed
- 15
- Starts
- 2011-01-01
- Expected to finish
- 2012-06-01
- Last updated by the study team
- 2014-04-15
Who can join
Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- healthy volunteers
- no history of depression or pain
- no metal in body
- no medications that lower seizure threshold
You may not qualify if…
- history of depression or pain
- history of seizures or epilepsy
- metal implants in body
- medications that lower seizure threshold
- psychiatric medications
Where it is running
- Medical University of South Carolina — Charleston, South Carolina, United States
Full record on ClinicalTrials.gov
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