Antithrombotic Effects of Ticagrelor Versus Clopidogrel

Completed · Phase 4

Conditions studied: Acute Coronary Syndrome

In brief

The purpose of this study is to determine whether treatment with ticagrelor (plus aspirin and bivalirudin) is more effective than treatment with clopidogrel (plus aspirin and bivalirudin).

Key facts

Study ID

NCT01642238

Run by

Juan J Badimon

People needed

15

Starts

2012-07-01

Expected to finish

2013-04-01

Last updated by the study team

2016-07-11

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male or female volunteers between 18 and 65 years old.
• Body mass index (BMI) 18 - 30 kg/m2 inclusive.
• Healthy as assessed by a detailed medical history and physical examination.
• Laboratory est results within the normal range.
• Ability to provide signed informed consent.

You may not qualify if…

• History of clinically relevant disease, bleeding, acute infectious disease or signs of acute illness.
• Allergy or hypersensitivity to aspirin or thienopyridines, or atopy diagnosed by a physician.
• Use of medication within one month prior to study drug administration.
• History of drug abuse or alcohol consumption >20 g/day.
• Inability to abstain from intensive muscular effort or sport competition.
• Loss of >400 mL blood or blood donation within 3 months.
• Positive serology for hepatitis B (HBs Ag) or hepatitis C.
• Conditions associated with hemorrhagic risk.
• Positive pregnancy test.

Where it is running

• Icahn School of Medicine at Mount Sinai — New York, New York, United States

Full record on ClinicalTrials.gov

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