Studying Biomarkers in Samples From Younger Patients With Acute Myeloid Leukemia

Completed

Conditions studied: Childhood Acute Monoblastic Leukemia (M5a), Childhood Acute Monocytic Leukemia (M5b), Childhood Acute Myeloblastic Leukemia Without Maturation (M1), Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies, Childhood Acute Myelomonocytic Leukemia (M4)

In brief

This laboratory study is looking into biomarkers in samples from younger patients with acute myeloid leukemia. Studying samples of bone marrow from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer

Key facts

Study ID

NCT01642121

Run by

Children's Oncology Group

People needed

20

Starts

2012-08-01

Last updated by the study team

2016-05-19

Who can join

Age: any, up to 30. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Frozen bone marrow aspirates obtained from childhood acute myeloid leukemia (AML) patients possessing defined cytogenetic mutations; AML1-ETO or inv(16)
• Samples of cytogenetically normal AML cases obtained from the University of Alabama at Birmingham (UAB) as controls

Where it is running

• Children's Oncology Group — Monrovia, California, United States

Full record on ClinicalTrials.gov

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