Intestinal Permeability in Response to Treatment in Eosinophilic Esophagitis Patients

Completed · Phase 1

Conditions studied: Eosinophilic Esophagitis

In brief

Do patient's with eosinophilic esophagitis have increased small intestinal permeability and if this changes in response to topically administered esophageal steroids?

Key facts

Study ID

NCT01641913

Run by

Mayo Clinic

People needed

20

Starts

2012-08-01

Expected to finish

2014-02-01

Last updated by the study team

2014-06-24

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects between the ages of 18 and 80 with Eosinophilic Esophagitis diagnosed by compatible symptoms, endoscopic findings, histology and lack of response to proton pump inhibitors or negative pH study.
• Exclusion:
• Vulnerable populations, such as those with diminished mental acuity, will be excluded.
• Patients allergic to Lactulose
• Women who are pregnant or lactating.

Where it is running

• Mayo Clinic in Rochester — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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