An HIV Intervention for Black Men at Risk - The Enhanced Sexual Health Intervention for Men (ES-HIM)
Completed · Phase 2
Conditions studied: HIV, Depression, Posttraumatic Stress Disorder
In brief
HIV continues to spread among Black men who have sex with men (MSM), but few interventions target high-risk Black men who have sex with men and women (MSMW). Black MSMW with histories of childhood sexual abuse (CSA) may be an especially vulnerable population for: a) high-risk sexual behaviors; b) negative psychological sequelae (e.g., depressive or posttraumatic stress disorder (PTSD) symptoms); and c) neurobiological abnormalities in cardiovascular, neuroendocrine and/or immune systems (e.g., cortisol and norepinephrine), and HIV/AIDS progression. The purpose of this study was to test an HIV risk reduction intervention, guided by the Social Learning Theory, the Ecological Model, and the concept of allostatic load, a composite of the cumulative effects of stress on biological systems including psychoneuroimmunologic markers. The investigators tested the 6-session Enhanced Sexual Health Intervention for Men (ES-HIM) on 88 non-gay identifying HIV-positive Black MSMW with histories of CSA. The outcomes were to reduce high-risk sexual behaviors (i.e., unprotected anal and vaginal sex and number of sex partners) and negative psychological symptoms of depression and PTSD. Links between these outcomes and biomarkers of stress were also explored. Randomization to either the ES-HIM or a health promotion control group occurred with study participants assessed at baseline, post, 3- and 6-months.
Key facts
- Study ID
- NCT01641146
- Run by
- University of California, Los Angeles
- People needed
- 118
- Starts
- 2008-12-01
- Expected to finish
- 2011-05-01
- Last updated by the study team
- 2016-11-28
Who can join
Age: 18 and older. Sex: male. Healthy volunteers: accepted.
You may qualify if…
- At least 18 years of age
- Male
- English speaking
- HIV-positive
- non-gay identifying
- Black/African American
- Sexually active and engaged in unprotected anal and/or vaginal sex with both a male and female partner in the previous 90 days
- Have a history of child sexual abuse
You may not qualify if…
- Younger than 18 years of age
- Female
- Non-English speaking
- HIV-negative or unknown HIV-serostatus
- Race/Ethnicity other than Black / African American
- Not sexually active, uses condoms and/or lacks both male and female partners in past 90 days
- No history of child sexual abuse
Where it is running
- The AmASSI Health and Cultural Center — Inglewood, California, United States
- Palms Residential Care Facility — Los Angeles, California, United States
- University of California, Los Angeles (UCLA) — Los Angeles, California, United States
- JWCH Institute Inc. — Los Angeles, California, United States
Full record on ClinicalTrials.gov
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