Walnuts and Healthy Aging

Completed · Not applicable

Conditions studied: Age Related Cognitive Decline, Age Related Macular Degeneration

In brief

This will be a systematic investigation of the role of walnuts in preventing or slowing age related cognitive decline and age related macular degeneration. 700 subjects will be recruited between 2 sites, Loma Linda University in California, USA and Hospital Clinic in Barcelona, Spain. Participants will be randomly assigned to either the walnut group or the control group for a 2 year intervention. Baseline and annual data will be collected and analyzed.

Key facts

Study ID: NCT01634841
Run by: Loma Linda University
People needed: 708
Starts: 2012-04-01
Expected to finish: 2016-05-01
Last updated by the study team: 2021-06-24

Who can join

Age: 63 and older, up to 79. Sex: any. Healthy volunteers: accepted.

You may qualify if…

63 to 79 years old
healthy men and women
able to attend clinic at a study sites

You may not qualify if…

illiteracy or inability to understand the protocol
unable to undergo neurophysiological tests
morbid obesity (BMI greater than or equal to ≥ 40 kg/m2)
uncontrolled diabetes (HbA1c>85)
uncontrolled hypertension
prior cerebrovascular accident
any relevant psychiatric illness, including major depression
advanced cognitive deterioration, dementia
other neurodegenerative diseases (i.e. Parkinson's disease)
any chronic illness expected to shorten survival (heart, liver, cancer, etc)
bereavement in the first year of loss
bad dentures unless fixable dental prostheses are used
allergy to walnuts
customary us of fish oil or flaxseed oil supplements
eye related exclusion criteria

Where it is running

Loma Linda University, Department of Nutrition — Loma Linda, California, United States
Hospital Clinic, University of Barcelona — Barcelona, Spain

Full record on ClinicalTrials.gov

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