A Multiple-dose Study of LY3031207 in Healthy Participants
Stopped early · Phase 1 · Has a placebo group
Conditions studied: Healthy Volunteers
In brief
The purposes of this study are to look at safety, how well the study drug is tolerated, how much of the study drug gets into the blood stream, and how long it takes the body to get rid of it when given to healthy Japanese and non-Japanese participants as multiple doses. In addition, effects of 28-day oral dosing of LY3031207 on the amount of a cholesterol-lowering drug (simvastatin) that gets into the blood stream and how long the body takes to get rid of it will be determined. The effects of LY3031207 after single and 28-day dosing on blood pressure will also be studied. Information about any side effects that may occur will be collected.
Key facts
- Study ID
- NCT01632566
- Run by
- Eli Lilly and Company
- People needed
- 39
- Starts
- 2012-06-01
- Expected to finish
- 2013-04-01
- Last updated by the study team
- 2019-06-27
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Overtly healthy individuals based on the history and physical examinations as determined by the investigator, including first generation Japanese
- Body mass index between 17.0 and 32.0 kilograms per square meter (kg/m\^2), inclusive
You may not qualify if…
- Have known allergies to LY3031207 or any components of the formulation, simvastatin or related compounds (other 3-Hydroxy-3-Methyl-Glutaryl-CoA [HMG CoA] reductase inhibitors), celecoxib, or sulfonamides. Participants with known aspirin allergy or allergic reaction to nonsteroidal anti-inflammatory drugs (NSAIDs) should also be excluded
Where it is running
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. — Honolulu, Hawaii, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.