Cognitive-Behavioral Therapy for Irritability in Adolescents With High Functioning Autism Spectrum Disorder

Completed · Not applicable

Conditions studied: Autism, Autism Spectrum Disorder (ASD, Asperger's Disorder, Pervasive Developmental Disorder (PDD-NOS)

In brief

In addition to the core symptoms, children and adolescents with Autism Spectrum Disorder (ASD) often exhibit disruptive behavior problems including irritability, tantrums, noncompliance, and aggression. This is a pilot study of Cognitive-Behavioral Therapy, also known as Anger Control Training, in adolescents with high-functioning ASD. CBT teaches children to recognize antecedents and consequences of problem behavior and to use emotion regulation and problem-solving skills to reduce irritability, aggression and noncompliance. This form of CBT has been well-studied in typically developing children with disruptive behavior and we are investigating if this treatment can be feasible and helpful, with appropriate modifications, for irritability and disruptive behavior in ASD.

Key facts

Study ID

NCT01631851

Run by

Yale University

People needed

9

Starts

2011-05-01

Expected to finish

2013-04-23

Last updated by the study team

2023-11-18

Who can join

Age: 9 and older, up to 16. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• DSM-IV diagnosis of autistic disorder, Asperger's disorder, or PDD-NOS
• presence of disruptive behaviors such as irritability and anger outbursts
• IQ above 80
• Unmedicated or on stable medication

You may not qualify if…

• medical or psychiatric condition that would require alternative treatment

Where it is running

• Yale Child Study Center — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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