A Study Of PF-00547659 In Patients With Moderate To Severe Ulcerative Colitis

Completed · Phase 2 · Has a placebo group

Conditions studied: Ulcerative Colitis

In brief

To determine the dose or doses of PF-00547659 that will be the most effective to improve or halt the disease symptoms in patients with moderate to severe ulcerative colitis.

Key facts

Study ID

NCT01620255

Run by

Shire

People needed

357

Starts

2012-11-02

Expected to finish

2016-02-04

Last updated by the study team

2021-06-11

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects with diagnosis of Ulcerative Colitis for 3 or more months.
• Ulcerative colitis must be active beyond the rectum.
• Must active Ulcerative Colitis with a Total Mayo Score of 6 to 12 points

You may not qualify if…

• Pregnant or breast feeding.
• Diagnosis of indeterminate colitis or Crohn's Disease
• Subjects with history of colonic or small bowel obstruction or resection.

Where it is running

• UCSD Health System-Pharmacy only — La Jolla, California, United States
• Clinical and Translational Research Institute — La Jolla, California, United States
• Perlman Medical Offices — La Jolla, California, United States
• Thornton Hospital — La Jolla, California, United States
• Community Clinical Trials — Orange, California, United States
• GastroDiagnostics - Community Clinical Trials Drug — Orange, California, United States
• Rocky Mountain Clinical Research, LLC. — Denver, Colorado, United States
• Clinical Research of the Rockies — Lafayette, Colorado, United States
• Rocky Mountain Gastroenterology Associates — Thornton, Colorado, United States
• Endoscopy Center of Connecticut, LLC — Guilford, Connecticut, United States
• Endoscopy Center of Connecticut, LLC — Hamden, Connecticut, United States
• Gastroenterology Center of Connecticut, PC — Hamden, Connecticut, United States
• Medical REsearch Center of CT Drug — Hamden, Connecticut, United States
• Medical Research Network of Connecticut — Hamden, Connecticut, United States
• Florida Surgery Center — Altamonte Springs, Florida, United States
• Gastroenterology Associates — Crystal River, Florida, United States
• Research Consultant Group — Hialeah, Florida, United States
• Th Palmetto Surgery Center — Hialeah, Florida, United States
• Citrus Memorial Hospital — Inverness, Florida, United States
• Inverness Medical Imaging — Inverness, Florida, United States
• Nature Coast Clinical Research — Inverness, Florida, United States
• Suncoast Endoscopy Center — Inverness, Florida, United States
• Sand Lake Imaging — Maitland, Florida, United States
• Sylvester Comprehensive Cancer Center — Miami, Florida, United States
• Mayo Clinic Arizona — Scottsdale, Arizona, United States

Full record on ClinicalTrials.gov

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