Continuous Renal Replacement Therapy in the Setting of Orthotopic Liver Transplant

Withdrawn before enrolling · Not applicable

Conditions studied: Acute Kidney Injury, Liver Disease, Chronic Kidney Disease, End Stage Kidney Disease

In brief

To evaluate the efficacy of continuous renal replacement therapy (CRRT) during orthotopic liver transplantation (OLT) in clearing excess solutes and improving acid-base parameters. The investigators hypothesize that the use of intra-operative CRRT in OLT recipients is associated with increased solute removal and improved acid-base statues when compared to controls who do not receive CRRT

Key facts

Study ID

NCT01619449

Run by

University of Chicago

People needed

0

Starts

2012-04-01

Expected to finish

2014-12-01

Last updated by the study team

2015-05-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 18 or older and able to sign consent (or surrogate)
• Receiving liver or combined liver-kidney transplant
• eGFR < or equal to 40 ml/min immediately prior to transplant or currently on any form of renal replacement therapy for acute kidney injury or end-stage renal disease
• Pre-operative potassium of < or equal to 5.5 mEq/L

You may not qualify if…

• Pre-operative hemoglobin < or equal to 7 g/dL
• Pre-operative weight > or equal to 125 kig

Where it is running

• University of Chicago Medicine — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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