Amino Acid Supplementation in Recovery From Severe Burns

Completed · Not applicable · Has a placebo group

Conditions studied: Burn Injury

In brief

Exercise during recovery is now Standard of Care at Shriners Hospital for Children Galveston, since positive effects of exercise training were found on lean body mass and recovery after burns. Essential amino acids (EAA) effective in healthy individuals.Thus, EAA supplementation in children recovering from burns, may potentially augment the effects of exercise by increase muscle mass, improve muscle fat oxidation, reduce tissue fat, and possibly improve insulin resistance.

Key facts

Study ID

NCT01618630

Run by

The University of Texas Medical Branch, Galveston

People needed

20

Starts

2012-05-01

Expected to finish

2017-12-05

Last updated by the study team

2018-12-11

Who can join

Age: 7 and older, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female
• 7-17 years old
• Body weight >20 kg (based on blood requirements)
• ≥30% Total Body Surface Area (TBSA)
• Wounds 95% healed

You may not qualify if…

• Respiratory insufficiency
• Multiple fractures
• History of Cancer in the last 5 years
• Diabetes Mellitus
• Bilirubin > 3 mg/dl
• Associated head injuries requiring specific therapy
• Associated injuries to chest or abdomen requiring surgery
• Serum creatinine > 3 mg/dl after fluid resuscitation
• Receipt of any experimental drug other than the ones supplied within two months of this study
• Any metal in body including rods, cardiac defibrillator, pacemakers, etc
• Orthopedic casting which would prevent placement of patient in MRI machine
• Hepatitis
• Abnormal EKG
• Electrical burns
• Patients unable to lie still without heavy sedation will be excluded from MRI portion.

Where it is running

• Shriners Hospitals for Children — Galveston, Texas, United States

Full record on ClinicalTrials.gov

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