A Comparison of the Effects on Cardiovascular Risk Factors of Korean and American Dietary Profiles

Completed · Not applicable

Conditions studied: Hypercholesterolemia

In brief

The primary aim of this study is to compare, in a group of at-risk individuals, the role of three dietary patterns on indices of Cardiovascular Disease (CVD) risk: a) the recommended Korean pattern; b) the typical American diet, based on national dietary intake surveys; and c) the 2010 DGA diet pattern. A secondary aim will be to assess the effects of each diet on intestinal microbiota and on inflammatory biomarkers.

Key facts

Study ID

NCT01617525

Run by

USDA Beltsville Human Nutrition Research Center

People needed

29

Starts

2012-01-01

Expected to finish

2012-05-01

Last updated by the study team

2016-05-11

Who can join

Age: 25 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Non Asian-American men and women between the ages of 25-65 years
• Body Mass Index (BMI) ≥ 25 and ≤ 38 kg/m2
• Fasting LDL-cholesterol ≥ 130 mg/dL
• Willingness and ability to make scheduled appointments at clinical site as required by study protocol

You may not qualify if…

• Major aversions to Korean foods
• Known food allergies that would interfere with study protocol
• Use of cholesterol-lowering medication or dietary supplements
• Use of blood pressure medications
• Use of prebiotics or probiotics in the last 3 months
• Received medication for bacterial infection (antibiotic) in the last 3 months
• Regular use of fiber supplements or laxatives
• Conditions requiring ongoing medical care and/or medication, including kidney, liver, gastrointestinal or endocrine disorders.
• Regular tobacco use within 6 months prior to the start of the study
• History of eating disorders or other dietary patterns which are not consistent with the dietary intervention (e.g., vegetarians, very low fat diets, high protein diets)
• Voluntary or involuntary weight loss of 10% of body weight within the last 12 months
• Self-report of alcohol or substance abuse within the past 12 months
• Donated blood during the 8 week period prior to the study
• Other medical, psychiatric, or behavioral factors that in the judgment of the Principal Investigator may interfere with study anticipation or the ability to follow the intervention protocol

Where it is running

• USDA Beltsville Human Nutrition Research Center — Beltsville, Maryland, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.