Interstitial Cystitis: Elucidation of the Psychophysiologic and Autonomic Characteristics (ICEPAC) Study
Completed
Conditions studied: Interstitial Cystitis/Painful Bladder Syndrome, Myofascial Pelvic Pain
In brief
Interstitial cystitis/painful bladder syndrome (IC/PBS) causes severe bladder pain and extensive disability in a large group of women int he prime of their productive lives. Extensive study of the bladder itself has uncovered many abnormalities, but the investigators do not know if these are the cause or result of the disorder. None of these has led to any real long-term progress in treatment, so far. The investigators have found that other autonomic disorders often occur in both the patients themselves and in the family members of patients with IC/PBS. The investigators therefore propose to determine whether the main abnormality in IC/PBS actually lies in the autonomic nervous system, rather than the bladder. The investigators will do this through careful measurements of autonomic function and sensation in patients who have IC/PBS, both at rest, and under controlled psychological stress. The investigators will compare their measurements to patients with myofascial pelvic pain, to know which abnormalities are truly linked to IC/PBS, and which simply reflect the presence of pelvic pain.
Key facts
- Study ID
- NCT01616992
- Run by
- Case Western Reserve University
- People needed
- 200
- Starts
- 2009-09-01
- Expected to finish
- 2014-12-01
- Last updated by the study team
- 2015-02-04
Who can join
Age: 18 and older, up to 80. Sex: female. Healthy volunteers: accepted.
You may not qualify if…
- Pelvic surgery within the last 12 months
- Pelvic injection with the last 90 days
- Presence of IC/PBS by the current NIDDK criteria
Where it is running
- Summa Health System — Akron, Ohio, United States
- University Hospitals Case Medical Center — Cleveland, Ohio, United States
Full record on ClinicalTrials.gov
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