Analgesic Benefits of Perineural Versus Intravenous Dexamethasone in Patients Receiving Sciatic Nerve Block

Completed · Phase 4

Conditions studied: Fracture of Ankle

In brief

Patients scheduled to have foot and ankle surgery will typically receive a single shot sciatic nerve block to serve as the primary anesthetic and as part of a multi-modal post-operative analgesic plan. The investigators are investigating the use of perineural dexamethasone together with local anesthetics can improve the quality of recovery for patients receiving sciatic nerve blocks for foot and ankle surgery.

Key facts

Study ID

NCT01616173

Run by

Northwestern University

People needed

80

Starts

2012-06-01

Expected to finish

2013-06-01

Last updated by the study team

2014-11-20

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ASA 1-3 patients who are presenting for foot and ankle surgery and are candidates for a single injection sciatic nerve block to provide postoperative analgesia.
• Surgery confined to the foot and ankle.
• Patients aged 18-70 years.

You may not qualify if…

• ASA Classification of 4 or higher.
• Pre-existing neuropathy
• Coagulopathy
• Infection at the site
• Diabetes
• Non-English speaking or reading patients
• Systemic use of corticosteroids within 6 months of surgery
• Chronic opioid use
• Pregnancy
• Large (>3cm) skin incision around the medial aspect of the foot
• Any other contra-indication to regional anesthesia

Where it is running

• Northwestern University, Feinberg School of Medicine — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.