Delayed Start to Ovarian Stimulation

Stopped early · Phase 4

Conditions studied: Diminished Ovarian Reserve, Infertility, In Vitro Fertilization

In brief

In couples with infertility secondary to Diminished Ovarian Reserve, the investigators hypothesize that a delayed start (7 day) to ovarian stimulation with an GnRH antagonist (Ganirelix) will improve oocyte maturation and quality, and improve pregnancy outcomes.

Key facts

Study ID

NCT01614067

Run by

University of California, San Francisco

People needed

30

Starts

2012-05-01

Expected to finish

2014-09-01

Last updated by the study team

2021-06-15

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Antral Follicle Count (AFC) less than or equal to 4 as measured by transvaginal ultrasound (TVUS), or
• Cancellation of a prior IVF cycle due to poor ovarian response.
• Patients will receive an antagonist stimulation protocol for IVF, or IVF with Intracytoplasmic Sperm Injection (ICSI).

You may not qualify if…

• Severe male factor infertility requiring surgical intervention to obtain sperm
• Major uterine abnormality,
• Preimplantation genetic diagnostic (PGD) testing,
• Planned cycles without embryo transfer (for example, freeze-all, donor, or surrogate cycles).

Where it is running

• UCSF Center for Reproductive Health — San Francisco, California, United States

Full record on ClinicalTrials.gov

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