Saturated Fat Versus Monounsaturated Fat and Insulin Action

Completed · Not applicable

Conditions studied: Obesity

In brief

High intakes of saturated fat are associated with diabetes. Our work has shown that the two most common fatty acids in the North American diet, palmitic acid (saturated fat) and oleic acid (monounsaturated fat) are metabolized differently and have opposite effects on fat burning. The proposed study will examine biochemical and molecular mechanisms for how a high saturated fat diet versus a low saturated fat/high monounsaturated fat diet alters the action of the hormone, insulin, in skeletal muscle.

Key facts

Study ID

NCT01612234

Run by

University of Vermont

People needed

70

Starts

2010-04-01

Expected to finish

2015-11-01

Last updated by the study team

2015-12-02

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• healthy young adults,
• 18 - 40 years of age

You may not qualify if…

• regular aerobic exercise training,
• dyslipidemia, and
• type 2 diabetes or insulin resistance

Where it is running

• The Unversity of Vermont Clinical Research Center at Fletcher Allen Health Care — Burlington, Vermont, United States

Full record on ClinicalTrials.gov

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