Reducing Disparities in Primary Prevention of Cardiovascular Disease
Completed · Not applicable
Conditions studied: Cardiovascular Diseases, Cholesterol, LDL
In brief
Cardiovascular disease (CVD) is the leading cause of disparities in years of life lost by race and low socioeconomic status. Statins have been shown to decrease the risk of cardiovascular events among individuals with high CVD risk. Yet, despite increased statin use and overall declining CVD rates, disparities in statin use and disparities in the control of high cholesterol by race, ethnicity, and socioeconomic status have persisted. Objective: To improve the appropriate use of statins for primary cardiovascular disease prevention among high risk individuals at community health centers through a system of population health management that uses electronic health record (EHR) data to identify patients for targeted education and outreach. Aim 1: Conduct a randomized controlled trial among individuals with 10-year risk for myocardial infarction or coronary death of 10% or higher to determine if the population health management intervention, compared to usual care, results in higher rates of documented statin treatment discussions within 6 months (primary process outcome), higher rates of statin prescribing within 6 months (secondary process outcome), and higher rates of significant low-density lipoprotein cholesterol (LDL-C) lowering defined as a follow up LDL-C ≥30 mg/dL lower than baseline (primary clinical outcome). Aim 2: Interview patients who received the intervention to identify barriers to success Aim 3: Assess the overall costs of the intervention and the costs per each patient who achieves significant LDL-C lowering compared to patient who received usual care.
Key facts
- Study ID
- NCT01610609
- Run by
- Northwestern University
- People needed
- 646
- Starts
- 2012-06-01
- Expected to finish
- 2014-07-01
- Last updated by the study team
- 2014-09-29
Who can join
Age: 35 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- men >= 35 and women >= 45 years old
- LDL-C completed in the past 5 years
- Not currently prescribed lipid lowering medication
- >= 1 face to face visit to a study site in the 6 months prior to the start of the study or a visit during the enrollment period
- The 10-year risk of coronary death or myocardial infarction (based on Framingham Risk Score) is at least 10% and the LDL-C is above 100 mg/dL
You may not qualify if…
- Previously diagnosed with any of the following: coronary disease, peripheral arterial disease, carotid artery disease, abdominal aortic aneurysm, or diabetes mellitus
- Primary language is not English or Spanish
Where it is running
- North Country Health Care — Flagstaff, Arizona, United States
- Near North Health Service Corporation — Chicago, Illinois, United States
- Heartland Health Outreach — Chicago, Illinois, United States
Full record on ClinicalTrials.gov
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