Vilazodone for Treatment of Geriatric Depression

Completed · Phase 4

Conditions studied: Major Depressive Disorder

In brief

The purpose of this study is to examine the effects of vilazodone for the treatment of depression in older adults.

Key facts

Study ID

NCT01608295

Run by

University of California, Los Angeles

People needed

65

Starts

2012-07-01

Expected to finish

2015-09-01

Last updated by the study team

2018-05-11

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 60 years of age or older
• The presence of a major depressive disorder diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria
• A 24-item Hamilton Depression Rating Scale (HAMD) score of 17 or higher at baseline
• Mini-Mental State Exam (MMSE) score > 24.

You may not qualify if…

• Subjects will be excluded if they had any current and/or lifetime history of other psychiatric disorders (except unipolar depression with or without comorbid generalized anxiety disorder), or recent unstable medical or neurological disorders; any disabilities preventing their participation in the study; diagnosis of mild cognitive impairment (MCI)/dementia; those with known allergic reactions to paroxetine or vilazodone.

Where it is running

• UCLA Semel Institute — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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