Effects of Pulmonary Vasodilation Upon VA Coupling in Fontan Patients

Withdrawn before enrolling · Phase 3

Conditions studied: Congenital Heart Disease, Fontan

In brief

The study involves documenting the effects of inhaled nitric oxide upon ventricular-arterial coupling in patients with congenital heart disease and passive pulmonary blood flow. Consenting patients undergoing a clinically-indicated cardiac catheterization will be given inhaled nitric oxide for 10 minutes while intraventricular pressure-volume analysis will be make via conduction catheters.

Key facts

Study ID

NCT01607983

Run by

University of California, San Francisco

People needed

0

Starts

2012-06-01

Expected to finish

2017-12-01

Last updated by the study team

2018-05-04

Who can join

Age: 4 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All consecutive patients with single ventricle hearts having passive pulmonary blood flow presenting to the cardiac catheterization laboratory for clinically indicated cardiac catheterization.

You may not qualify if…

• Patients with coarctation of the aorta or known bilateral femoral arterial obstruction
• Patients with known severe systemic venous/Fontan obstruction
• Patients already receiving sildenafil or other vasodilator therapy

Where it is running

• University of California, San Francisco — San Francisco, California, United States

Full record on ClinicalTrials.gov

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