Gene Expression Profile After Gonadotropin Releasing Hormone (GnRH) Agonist Trigger of Oocyte Maturation

Stopped early · Phase 4

Conditions studied: Endometrial Receptivity, Ovarian Hyperstimulation Syndrome

In brief

The purpose of this study is to compare gene expression profiles in endometrial biopsies during the window of implantation after triggers of oocyte maturation using GnRH agonist or hCG and compared with their natural cycles in order to identify genes that may be dysregulated in GnRH agonist-triggered cycles. The investigators also intend to evaluate patients feeling of well being and physical quality of life after GnRH agonist trigger compared with hCG trigger.

Key facts

Study ID

NCT01606709

Run by

UConn Health

People needed

7

Starts

2012-04-01

Expected to finish

2014-12-01

Last updated by the study team

2018-11-21

Who can join

Age: 21 and older, up to 33. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Oocyte donors
• Ages between 21 and 33
• Normal baseline serum FSH < 10mIU/mL

You may not qualify if…

• Hypothalamic dysfunction
• Smokers
• Baseline serum FSH ≥ 10mIU/mL

Where it is running

• UCHC Division of Reproductive Endocrinology — Farmington, Connecticut, United States

Full record on ClinicalTrials.gov

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