Neural Activation and Connectivity in Response to Exercise and Cognitive Training

Completed

Conditions studied: Neural Connectivity

In brief

The goal of this pilot study is to evaluate whether healthy, sedentary older adults have increased activation of specific brain areas, in response to exercise and cognitive training, in comparison to a control group, and whether improvements in psychometric test performance are related to increased activation of brain networks. Participants, between age 55-75 years will be recruited from an ongoing study of exercise and cognitive training, to undergo Blood Oxygen Level Dependent (BOLD) functional magnetic imaging (fcMRI).

Key facts

Study ID

NCT01603771

Run by

Washington University School of Medicine

People needed

24

Starts

2011-06-01

Expected to finish

2012-12-01

Last updated by the study team

2014-09-03

Who can join

Age: 55 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• meet the inclusion criteria for the parent study, Combining Exercise and Cognitive Training to Improve Everyday Function (EXACT) study (Unique Protocol ID 201102416).

You may not qualify if…

• currently taking chronic psychotropic medication, beta blockers, or calcium channel blockers
• contraindication to MRI scanning
• inability to complete MRI scans in closed scanner

Where it is running

• Washington University School of Medicine — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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