Association Between a Mother's Exposure to "Strep Throat" and Her Baby's Developing Heart Disease

Completed

Conditions studied: Congenital Heart Disease in Pregnancy

In brief

The goal of this study is to find out if there is any association between a mother's exposure to bacteria that normally causes "strep throat" and her baby's developing heart disease/heart defect.

Key facts

Study ID

NCT01603732

Run by

Washington University School of Medicine

People needed

397

Starts

2010-01-01

Expected to finish

2015-12-01

Last updated by the study team

2017-04-04

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• For Fetal pts:
• HLHS or variant diagnosis
• Other Congenital Heart Disease
• Greater than or = 20wks gestation
• For Healthy moms:
• No diagnosis of Congenital Heart Disease
• Greater than or = 20wks gestation

You may not qualify if…

• For fetal pts \& healthy controls:
• Mom less than 18 years old
• Twins or multiple gestations
• Pregnancy affected by 2 or more congenital anomalies( in addition to heart defects)
• Pregnancy affected by OB complications like pre-eclampsia
• Known history of chromosomal anomaly or carrier status
• Pregnancy result of fertility treatment including in vitro fertilization
• Emotionally distress
• Mom received blood transfusion or immunoglobin infusion within 6 months of the pregnancy.

Where it is running

• St Louis Childrens Hospital — St Louis, Missouri, United States
• Cincinatti Children's Hospital Medical Center — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

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