Exercise Cardiac Magnetic Resonance Imaging Accuracy for Cardiovascular Stress Testing

Completed · Not applicable

Conditions studied: Coronary Artery Disease

In brief

This study is being done to demonstrate a powerful new method for detecting heart disease that combines the proven prognostic capability of exercise stress testing with the superior image quality of Cardiac Magnetic Resonance Imaging (CMR). The investigators hope to demonstrate that exercise CMR has equivalent or superior diagnostic accuracy compared to exercise stress SPECT for detecting obstructive artery disease.

Key facts

Study ID

NCT01592565

Run by

Ohio State University

People needed

227

Starts

2010-08-01

Last updated by the study team

2017-01-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• any patient referred for stress SPECT
• known or suspected ischemic heart disease
• ability to perform adequate treadmill stress

You may not qualify if…

• any contraindication to MRI (e.g. ferromagnetic foreign body, cerebral aneurysm clip, pacemaker/ICD, severe claustrophobia)
• renal insufficiency (GFR < 40)
• known allergy to gadolinium-based contrast or iodinated contrast (because of the research CTA (computed tomography angiography) in patients not referred for cath after 2 weeks)

Where it is running

• The Lindner Center at The Christ Hospital — Cinncinatti, Ohio, United States
• The Ohio State University — Columbus, Ohio, United States
• University Of Pittsburgh Medical Center — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

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