Inflammation and the Heart

Completed · Not applicable

Conditions studied: Rheumatoid Arthritis

In brief

Studies have shown that people with rheumatoid arthritis (RA) have a higher rate of heart disease than people that do not have RA. we believe this is caused by the inflammation produced by RA.

Key facts

Study ID

NCT01589770

Run by

Vanderbilt University

People needed

128

Starts

2012-08-01

Expected to finish

2015-01-01

Last updated by the study team

2019-05-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Written informed consent
• Age >= 18
• RA only: meet American College of Rheumatology(ACR)criteria for Diagnosis of RA
• Controls only: no evidence of RA or other inflammatory disease

You may not qualify if…

• Previous or current heart failure or ischemic cardiovascular disease (eg stroke, myocardial infarction, angina, CABG, stent).
• Atrial fibrillation.
• Known structural or functional cardiac abnormality, including pulmonary htn.
• Glomerular filtration rate < 60 ml/min.
• Pregnancy or breastfeeding.
• Unable to perform MRI (claustrophobia, unable to fit in magnet,pacemaker,defibrillator or non-MR safe implant).
• Hypersensitivity to gadolinium.

Where it is running

• Vanderbilt — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

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