Neuroblastoma Biology Study

Recruiting now

Conditions studied: Neuroblastoma

In brief

Medical scientists want to find better ways to treat neuroblastoma and to find ways to prevent the tumor from growing back. To do this, they need more information about the characteristics of neuroblastoma cells. Therefore, they want to study samples of neuroblastoma tissues and neuroblastoma and normal cells in the blood and bone marrow that may be related to the growth of neuroblastoma cells. Doctors and other medical scientists also want to find better ways to detect and measure neuroblastoma to improve the ability to follow the response of tumor cells to therapy.

Key facts

Study ID

NCT01587300

Run by

New Approaches to Neuroblastoma Therapy Consortium

People needed

1000

Starts

2011-07-01

Expected to finish

2099-12-01

Last updated by the study team

2026-03-23

Who can join

Age: 0 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients must be greater than or 31 days of age.
• Patients must have had a diagnosis of high risk neuroblastoma either by histological verification of neuroblastoma and/or demonstration of tumor cells in the bone marrow with increased urinary catecholamines.
• All patients with refractory or recurrent high risk neuroblastoma at NANT institutions are eligible regardless of disease status (including no measurable or evaluable tumor) as long as they undergo a disease evaluation and appropriate samples are submitted.
• Additionally, all patients with high risk neuroblastoma without relapse treated at a NANT institution are eligible if undergoing a disease evaluation, as long as Children's Oncology Group specimens are prioritized.

You may not qualify if…

• There are no exclusion criteria on this study.

Where it is running

• Children's Hospital Los Angeles — Los Angeles, California, United States (enrolling)
• Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States (enrolling)
• Cook Children's Medical Center - Fort Worth — Fort Worth, Texas, United States (enrolling)
• Seattle Children's Hospital — Seattle, Washington, United States (enrolling)
• Hospital for Sick Children — Toronto, Ontario, Canada (enrolling)
• UCSF Helen Diller Family Comprehensive Cancer Center — San Francisco, California, United States (enrolling)
• Children Hospital of Colorado — Aurora, Colorado, United States (enrolling)
• AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus — Atlanta, Georgia, United States (enrolling)
• University of Chicago, Comer Children's Hospital — Chicago, Illinois, United States (enrolling)
• Children's Hospital Boston — Boston, Massachusetts, United States (enrolling)
• C.S Mott Children's Hospital — Ann Arbor, Michigan, United States (enrolling)
• Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States (enrolling)
• Nationwide Children's Hospital — Columbus, Ohio, United States (enrolling)
• Lucille Salter Packer Children's Hospital, Stanford University — Palo Alto, California, United States
• University of North Carolina — Chapel Hill, North Carolina, United States
• University of Texas Southwestern — Dallas, Texas, United States
• St. Jude Children's Research Hospital — Memphis, Tennessee, United States

Full record on ClinicalTrials.gov

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