Microparticles in Scuba Divers With Decompression Sickness

Completed

Conditions studied: Decompression Sickness, Dysbarism

In brief

The investigators hypothesize that membrane microparticles (MPs) are liberated into the blood stream in response to decompression stress and that certain MPs characteristics initiate inflammatory responses that contribute to the clinical syndrome the investigators call decompression sickness. The research goal is to evaluate the number, type and time-course for elevations in MPs in sport SCUBA divers who present for treatment of decompression sickness. Blood samples are to be taken from consenting patients before and after they undergo treatment for decompression sickness and at a follow-up clinic visit from 1 to 3 weeks later (three samples total).

Key facts

Study ID

NCT01587209

Run by

University of Pennsylvania

People needed

1

Starts

2011-08-01

Expected to finish

2014-09-01

Last updated by the study team

2016-08-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients who are given the diagnosis of decompression sickness will be offered entry into this study

You may not qualify if…

• Inability to provide informed consent

Where it is running

• University of Pennsylvania — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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