Exercise in Breast Cancer Survivors

Withdrawn before enrolling · Not applicable

Conditions studied: Breast Cancer, Obesity

In brief

The investigators hypothesize that exercise in postmenopausal breast cancer survivors will result in an increase in the plasma concentrations of angiostatic factors and a decrease in the plasma concentrations of angiogenic factors. Exercise is expected to result in a circulating angiostatic phenotype that inhibits adipose tissue mass, growth of breast cancer tumor, growth of microscopic residual disease after breast cancer resection, decreases rates of local-regional recurrence, decreases rates of distant recurrence, and increases survival.

Key facts

Study ID

NCT01582685

Run by

University of Mississippi Medical Center

People needed

0

Starts

2012-04-01

Expected to finish

2014-06-01

Last updated by the study team

2014-12-02

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• > 18 years of age and < 65 years of age
• Female
• BMI > 25
• Weight < 350 pounds
• English as a primary language
• Postmenopausal
• Invasive ER-positive cancer on biopsy and subsequent definitive surgical therapy
• Received and Completed standard of care adjuvant therapy (Concurrent endocrine therapy acceptable)
• 6-12 months after completion of therapy (excluding adjuvant endocrine therapy) at time of randomization

You may not qualify if…

• Recurrent breast cancer
• DCIS only (no invasive component)
• Taking a Beta Blocker or Verapamil
• Pregnant
• Wheelchair bound
• Unable to ambulate independently
• Concurrent uncontrolled medical or psychiatric disorder
• Open wound
• Stage IV breast cancer
• Progression of disease
• Bilateral mastectomies

Where it is running

• University of Mississippi Health Care — Jackson, Mississippi, United States

Full record on ClinicalTrials.gov

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