Recording for Potential AF Drivers and Patient Specific Atrial Anatomy & Atrial Electrogram Maps
Completed · Not applicable
Conditions studied: Atrial Fibrillation
In brief
The 64 pole basket catheter used for the mapping procedure will be defined "atypical" sites which sustain atrial fibrillation. The ablation through the driver will lead to more rapid ablation of the atrial fibrillation.
Key facts
- Study ID
- NCT01581437
- Run by
- Virginia Commonwealth University
- People needed
- 78
- Starts
- 2011-10-01
- Expected to finish
- 2013-12-01
- Last updated by the study team
- 2016-03-11
Who can join
Age: 21 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients at VCU Medical Center who are 21 years or older undergoing EPS for ablation of persistent AF (non-rheumatic) whose AF episodes last equal to or greater than 7 days but terminate with DC cardioversion or anti-arrhythmic drugs and do not recur within 24 hours.
- Per current standard of care, AF patients must have failed equal to or greater than 1 anti-arrhythmic drug to qualify for ablation.
You may not qualify if…
- Active coronary ischemic in the past year
- Rheumatic valve disease, that leads to distinct AF and increases thromboembolic risk
- Prior ablation or cardiac surgery, that alters atrial electophysiology
- Left atrial clot or dense contrast on TEE, which would increase thromboembolic risk
- Out of range serum electrolytes, including K outside 4.0-5.0 mmol/1
- Left atrial diameter greater than 60 mm, to exclude extreme structural remodeling and failure to maintain sinus rhythm
- Thrombotic disease, venous filters, transient ischemic attack or cerebrovascular accident, to minimize additional risk
- Pregnancy
- Inability or unwillingness to provide informed consent
- Unable to converse in English
- Use of anti-arrhythmic drug less than 5 X half-life Prior ablation or cardiac surgery, that alters atrial electophysiology
Where it is running
- Virginia Commonwealth University — Richmond, Virginia, United States
Full record on ClinicalTrials.gov
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