Tumor Markers in Lung Cancer: DCAMLK-1LK-1

Completed · Not applicable

Conditions studied: Lung Cancer, Smoking

In brief

DCAMLK1 is a Ca2+ - ca/modulin (CaM) - dependent protein kinase that is a marker of stem cells in colonic crypts. Mutations within the stem cell population are thought to be responsible for the development of most colorectal carcinomas and studies have shown that DCAMLK1 is highly expressed in these tumors. Since the lung is an embryological development of the foregut, the investigators speculate that DCAMLK1 will also be upregulated in lung cancers. The aim of this pilot study is to measure DCAMLK1 levels in the blood of patients with suspected malignant and benign lung diseases, and to correlate DCAMKL1 levels with smoking status.

Key facts

Study ID

NCT01578018

Run by

University of Oklahoma

People needed

49

Starts

2011-12-01

Expected to finish

2012-07-01

Last updated by the study team

2012-08-10

Who can join

Age: 45 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• >45 years of age

You may not qualify if…

• Unable to provide informed consent

Where it is running

• VAMC-OKC — Oklahoma City, Oklahoma, United States

Full record on ClinicalTrials.gov

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