Hypotensive Effects of Conventional Dairy Products: Role of Arterial Stiffness

Completed · Not applicable

Conditions studied: Prehypertension, Stage-1 Hypertension

In brief

Elevated systolic blood pressure is by far the largest single contributor to cardiovascular risks in middle-aged and older adults. Lifestyle modifications, including dietary modifications, are the first line approach for treating and preventing hypertension. The general aim of the proposed study is to address the efficacy of conventional dairy products as part of the normal routine diet for lowing arterial blood pressure in middle-aged and older adults with elevated blood pressure. The investigators hypothesize that the dietary intervention including dairy products will induce significant decreases in arterial blood pressure in this population. A secondary aim will be to test the hypothesis that these reductions in systolic blood pressure will be associated with increases in arterial stiffness/compliance and endothelial vasodilatory function.

Key facts

Study ID

NCT01577030

Run by

University of Texas at Austin

People needed

49

Starts

2012-01-01

Expected to finish

2013-11-01

Last updated by the study team

2014-02-12

Who can join

Age: 35 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Prehypertension or stage-1 hypertension

You may not qualify if…

• Consume > 3 servings of dairy or fruit per day
• Strenuous physical activity > 3 time per week
• Lactose intolerance, pregnancy, lactation, and/or alcohol abuse
• Taking cardiovascular-acting drugs
• Overt cardiovascular disease, metabolic disease, GI disorders and/or renal disease

Where it is running

• The University of Texas at Austin, Cardiovascular Aging Research Laboratory — Austin, Texas, United States

Full record on ClinicalTrials.gov

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