Oral Trehalose Therapy to Reverse Arterial Aging in Middle-Aged and Older Adults

Completed · Not applicable · Has a placebo group

Conditions studied: Vascular Aging

In brief

The proposed study will assess the ability of a naturally occurring sugar to improve the function of arteries with age. Overall, the proposed research project has the long-term potential to influence clinical practice guidelines by establishing a novel, easy to deliver, cost-effective therapy for treating age-associated arterial dysfunction and reducing the risk of cardiovascular disease with age.

Key facts

Study ID

NCT01575288

Run by

University of Colorado, Boulder

People needed

110

Starts

2012-05-01

Expected to finish

2015-12-01

Last updated by the study team

2015-12-11

Who can join

Age: 50 and older, up to 79. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• women must be postmenopausal
• body mass index (BMI) <40 kg/m2
• weight stable in the prior 3 months
• absence of clinical disease as determined by medical history, physical examination, blood and urine chemistries, ankle-brachial index, and a graded exercise stress test with monitoring of blood pressure and 12-lead ECG

Where it is running

• University of Colorado, Boulder Clinical Translational Research Center — Boulder, Colorado, United States

Full record on ClinicalTrials.gov

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