The Neurobiology of Expectancy and Pain Perception

Completed · Not applicable

Conditions studied: Pain

In brief

This study will use using fMRI (functional Magnetic Resonance Imaging) to elucidate how contextual learning/expectation relieves or aggravates pain experience in the same cohort of subjects and the same study session.

Key facts

Study ID

NCT01575106

Run by

Massachusetts General Hospital

People needed

38

Starts

2012-06-01

Expected to finish

2013-10-01

Last updated by the study team

2017-10-13

Who can join

Age: 21 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• a) Healthy male and female adults aged 21-50
• b) No contraindications to fMRI scanning
• c) Right handed

You may not qualify if…

• a) Current or past history of major medical, neurological, or psychiatric illness
• b) Pregnancy or breast feeding, menopause, and irregular menstrual cycles (length of cycle must be within 26 to 32 days)
• c) Claustrophobia
• d) History of head trauma
• e) History of impaired elimination
• f) Instability of responses to experimental pain (see Study Procedures Section)
• g) Use of psychotropic drugs, hormone treatments (including hormonal birth control) within 1 year
• h) Non-fluent speaker of English

Where it is running

• Massachusetts General Hospital — Charlestown, Massachusetts, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.