Polar Body Biopsy for Preimplantation Genetic Screening

Completed · Not applicable

Conditions studied: Aneuploidy

In brief

People with infertility undergoing in vitro fertilization (IVF) can test the embryos using a method called preimplantation genetic screening (PGS) before they are implanted in the uterus to possibly increase their chances of having a successful pregnancy. One or more cells are removed from the embryo. The chromosomes inside the cells are then tested to identify normal or aneuploid embryo(s). The investigators propose to evaluate a test called micro array analysis on the chromosomes of the first polar body. This method tests part of the egg that would normally be lost and may help us choose the embryo most likely to become a healthy baby.

Key facts

Study ID

NCT01574404

Run by

Weill Medical College of Cornell University

People needed

33

Starts

2011-09-01

Expected to finish

2014-12-01

Last updated by the study team

2015-06-11

Who can join

Age: 18 and older, up to 42. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Are undergoing IVF/Intracytoplasmic sperm injection(ICSI)
• Are considering preimplantation genetic screening for aneuploidy
• Are between ages 18 and 42 inclusive (female partner)

You may not qualify if…

• Using sperm from a testicular source
• Fewer than 10 oocytes retrieved
• Fewer than 6 oocytes fertilized normally
• Complete fertilization failure (no oocytes fertilize)

Where it is running

• Ronald O. Perelmand and Claudia Cohen Center for Reproductive Medicine — New York, New York, United States

Full record on ClinicalTrials.gov

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