Conversations as a Means to Delay the Onset of Alzheimer's Disease

Completed · Early Phase 1

Conditions studied: Mild Cognitive Impairment, Cognitive Change

In brief

Past epidemiological studies have demonstrated that larger social networks, or more frequent social interactions, could have potential protective effects on the incidence of Alzheimer's Disease (AD). However, in those studies, indicators of social interactions were often broad, and included distinct elements that affected cognition and overall health. This project will examine whether conversation-based cognitive stimulation has positive effects on domain-specific cognitive functions among the elderly. Face-to-face communication will be conducted through the use of personal computers, webcams, and user-friendly simple interactive Internet programs to allow participants to have social engagement while staying at their home and also for the cost effective execution of the study.

Key facts

Study ID

NCT01571427

Run by

Oregon Health and Science University

People needed

83

Starts

2012-02-01

Expected to finish

2013-09-01

Last updated by the study team

2020-02-05

Who can join

Age: 70 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Non-demented participants
• Willing to participate in daily conversation using internet/webcam with interviewers for 6 weeks
• Willing to monitor daily conversational amount using a digital recording device
• Willing informant who has frequent contact with the participant

You may not qualify if…

• have major illness or disabilities which interfere with interacting using the audio/video technology
• diagnosed as dementia
• MMSE < 24 at screening
• Geriatric Depression Scale (15 items) >4 at screening

Where it is running

• Oregon Health & Science University — Portland, Oregon, United States

Full record on ClinicalTrials.gov

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