Role of Infected Blood Dendritic Cells in Heart Disease Risk

Completed · Not applicable

Conditions studied: Chronic Periodontitis

In brief

The investigators hypothesize that blood dendritic cells harbor pathogens from the oral cavity in chronic periodontitis and disseminate these pathogens to atherosclerotic plaques.

Key facts

Study ID

NCT01568944

Run by

Augusta University

People needed

18

Starts

2012-03-01

Expected to finish

2014-09-01

Last updated by the study team

2020-05-12

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• generalized moderate to severe chronic periodontitis

You may not qualify if…

• diabetes
• antibiotics treatment within 3 months
• treatment with steroids, phenytoin, cyclosporin, coumadin
• presence of conditions requiring prophylactic antibiotics per AHA
• cancer, HIV, hepB, lupus, prediagnosed heart disease, renal disease
• smoker

Where it is running

• GHSU-CDM Clinical Research Center — Augusta, Georgia, United States

Full record on ClinicalTrials.gov

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