Breast MRI for Newly Diagnosed Breast Cancer:Impact on Re-excision Lumpectomy

Stopped early · Phase 3

Conditions studied: Breast Cancer

In brief

This study is being done to find out the number of surgical procedures required to achieve clear margins in women with newly diagnosed early stage breast carcinoma. The investigators are also looking at the number of additional biopsies performed before surgery, the mastectomy rate, detection of breast cancer on the opposite side (contralateral carcinoma), time form diagnosis to local therapy, and evaluation time to local recurrence.

Key facts

Study ID: NCT01568346
Run by: Dana-Farber Cancer Institute
People needed: 9
Starts: 2012-02-01
Expected to finish: 2013-03-01
Last updated by the study team: 2016-08-02

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

Must undergo definitive local therapy with either breast conserving therapy or mastectomy
Clinical Stage 0, I or II breast cancer based on examination and/or conventional imaging of mammogram with or without ultrasound. Tumors must be less than 5 cm in size and the patient clinically node negative
Able to undergo breast MRI

You may not qualify if…

Not pregnant or breastfeeding
No prior breast MRI for the newly diagnosed carcinoma at the outside hospital
No prior mantle radiation
No locally advanced breast cancer
No diffuse malignant appearing microcalcifications requiring mastectomy
No known collagen vascular disease
No previous ipsilateral radiation
No participants who undergo surgery at an outside institution
No prior history of breast carcinoma

Where it is running

Brigham and Women's Hospital — Boston, Massachusetts, United States
Dana-Farber Cancer Institute — Boston, Massachusetts, United States
Faulkner Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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