Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas

Completed

Conditions studied: Childhood Alveolar Soft-part Sarcoma, Childhood Angiosarcoma, Childhood Desmoplastic Small Round Cell Tumor, Childhood Epithelioid Sarcoma, Childhood Fibrosarcoma, Childhood Leiomyosarcoma, Childhood Liposarcoma, Childhood Malignant Mesenchymoma, Childhood Neurofibrosarcoma, Childhood Synovial Sarcoma, Chordoma, Desmoid Tumor, Metastatic Childhood Soft Tissue Sarcoma, Nonmetastatic Childhood Soft Tissue Sarcoma, Recurrent Childhood Soft Tissue Sarcoma

In brief

This research trial studies genes in tissue samples from younger and adolescent patients with soft tissue sarcomas. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors find better ways to treat cancer

Key facts

Study ID

NCT01567046

Run by

Children's Oncology Group

People needed

70

Starts

2016-05-01

Expected to finish

2016-05-01

Last updated by the study team

2016-05-17

Who can join

Age: any, up to 30. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Archived non-rhabdomyosarcoma soft tissue sarcoma (NRSTS) tumor-derived DNA
• Synovial sarcoma, malignant peripheral nerve sheath tumor (MPNST), soft tissue sarcoma not otherwise specified (NOS), or other less common pediatric NRSTS
• Formalin-fixed, paraffin-embedded (FFPE) tissue from patients enrolled on:
• COG-D9902 Soft Tissue Sarcoma (STS) Biology and Banking Protocol
• COG-ARST0332 A Risk-Based Treatment for Pediatric NRSTS Study
• See Disease Characteristics

Where it is running

• Children's Oncology Group — Monrovia, California, United States

Full record on ClinicalTrials.gov

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