Pomegranate and Hemodialysis Pilot Trial
Completed · Not applicable
Conditions studied: End Stage Renal Disease, Cardiovascular Disease, Inflammation
In brief
In this study, the investigators will administer pomegranate juice or fruit extract as a targeted antioxidant therapy to hemodialysis patients. The investigators will examine whether these pomegranate products will be safe and well-tolerated. The investigators will also examine whether these products may lead to improvements in blood serum biomarkers of: * oxidative stress status * inflammatory status * endothelial dysfunction
Key facts
- Study ID
- NCT01562340
- Run by
- University of Washington
- People needed
- 24
- Starts
- 2012-03-01
- Expected to finish
- 2012-12-01
- Last updated by the study team
- 2015-05-28
Who can join
Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with end-stage renal disease receiving thrice weekly hemodialysis
- Age > 18 or < 85 years
- Life expectancy greater than one year
- Ability to understand and provide informed consent for participation in the study
You may not qualify if…
- History of poor adherence to hemodialysis or medical regimen
- Prisoners, patients with significant mental illness, and other vulnerable populations
- AIDS (HIV seropositivity is not an exclusion criteria)
- Active malignancy excluding basal cell carcinoma of the skin
- Gastrointestinal dysfunction requiring parenteral nutrition
- History of functional kidney transplant < 6 months prior to study entry
- Anticipated live donor kidney transplant
- Patients taking vitamin E supplements > 60 IU/day, vitamin C > 150 mg/day or other antioxidant or nutritional supplements
- Incident hemodialysis patients (defined as within 30 days of dialysis initiation)
- Patients hospitalized for more than 5 days within the past 30 days.
- Patients with a history of a major atherosclerotic event (defined as combined incidence of myocardial infarction, urgent target-vessel revascularization, coronary bypass surgery, and stroke) within three months
- Pregnancy
Where it is running
- Northwest Kidney Centers — Seattle, Washington, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.